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Advanced file upload

The structure of compressed file for advanced MINERVA upload

Advanced upload mode assumes that a zip-compressed directory will be submitted as an input, with the structure presented below. Note: There is no necessity to zip-compress all directories - upload to MINERVA an archive containing main map plus any of these directories works.

  • main map: file in a SBGN-compliant format (CellDesigner or SBML)
  • overlays: directory with overlay files (see Overlays)
  • glyphs: directory with glyphs (see Glyphs)
  • submaps: directory with submap files (see Submaps)
  • images: directory with files displayed as Show overview (see Images)


After upload, in Add project window additional tabs become available. Each tab represents subfolder of a source file, see below:

New zipped project
Learn more about advanced upload in example 04 - The advanced file upload.

Note: to export the map together with any subdirectory you need to get source file from Info tab .


Sections of the compressed file

Overlays

The layouts subdirectory contains files with custom colorings of the uploaded content that will be accessible to all the users. The format is identical to the format of files uploaded by registered users. See section Upload user provided overlay data for details on file format.

Glyphs

MINERVA allows to color the map’s elements (species, compartment, pathways) with the images provided by user (see image below). Note: MINERVA supports only extension for PNG.

Glyphs background

The archived file has to contain the images inside the glyphs directory. Particular elements have to contain below term so the glyph is displayed in MINERVA:
Glyph: glyphs/my-image.png
For species and compartments, input the term into their NOTE in CellDesigner. For pathways (CellDesigner text area) - double click on the text area to input the term.

Find more details about glyphs in the example 6 - Map with glyphs.


Submaps and mapping file

The submaps subdirectory contains files that will be displayed in the Submaps tab in the functional area of the User view (see section User view - Submaps tab). Additionally to the submaps files, one additional file - submap mapping file, can be added to the directory. This file describes connections between the submaps and the main map itself.

Submap mapping file is a CellDesigner file, in which relations between the uploaded maps are represented graphically. Two types of components and one type of interaction is considered when parsing this file:

  • State transition reaction describes relations between components of the map.

  • Complex should be named as a map file (the main map, or a submap), but without the .xml extension.

  • Protein should be named as an alias of referred element in the source file (the main map, or a submap). Please note that a species alias is not the same as a species identifier!

    Alias vs identifier remark: CellDesigner has a single species identifier for all copies of a certain element (e.g. protein) in a file. Different instances of the same element have a distinct species alias. It is the species alias that is used to link specific map elements with submaps.
    In CellDesigner, highlight a protein and press keys “Control + T” to display alias of an element (dialog, see below, will open). alias


Image below demonstrates an exemplary submap mapping file. Submaps Mapping Section Add project -> Submaps describes how main map and uploaded submaps are related, see image below:

  • File name: name of one of multiple files.

  • Name: name of the (sub)map in the project.

  • The dropdown list:

    • ROOT: one position must be checked and corresponds to the main map in the project.

    • MAPPING: one position must be checked and corresponds to the mapping file describing relationships between the main map and the submap(s).

    • Map types to choose: the submap can be a pathway, a list of downstream targets or unknown.

Submaps tab


Images

The images subdirectory contains static image files in .png format that will be displayed after pressing the Show overview button (see Show overview in User manual). Besides the images, the directory also has to contain a file describing links between the images and the associated network(s). This file must be a tab-separated text file named coords.txt or json file named coords.json.


The coords.txt file is a table with the following structure:

  • FILE - linked image file.

  • POLYGON - a sequence of points in the linked image file forming a polygon, which will be treated as an active area for the link. The points should be x,y pairs separated by a spacebar, representing absolute coordinates of the pixels in the corresponding image. They should be provided in a single line.

  • LINK_TYPE - the type of link to the image, has to be one of the types specified below; link type determines the usage of the remaining fields.

    • IMAGE - links to another image of the uploaded set.

    • MODEL - link to the main map, or one of the submaps.

    • SEARCH - link to the results of a search query.

  • LINK_TARGET - determined by the field LINK_TYPE.

    • if IMAGE - filename, must be one of the uploaded image files in the images directory.

    • if MODEL - filename of the uploaded main map, or one of the submaps.

    • if SEARCH - query to be executed and linked (see section Search in User manual).

  • MODEL_COORDINATES - if the field LINK_TYPE is MODEL, this field should contain absolute coordinates of the point in the target map, in the format x,y; otherwise it should be left empty.

  • MODEL_ZOOM_LEVEL - if the field LINK_TYPE is MODEL and absolute coordinates are given, this field should contain a number corresponding to the zoom levels in the display area; otherwise it should be left empty. The the furthest zoom out has number 0, each zoom in increases the zoom number by one. Smaller maps will have less zoom levels than big ones. Try uploading the map without images first, and assess the coordinates and zoom levels for the version with images.

  • COMMENT - a field for supplementary information, not used for configuration.


Example of a coords.txt file:

FILE POLYGON LINK_TYPE LINK_TARGET MODEL
_COORDINATES
MODEL
_ZOOM_LEVEL
COMMENT
image-A.png 51,218 107,218 107,252 51,252 MODEL PD_151023_1.xml 7488,11986 4 Link from image-A file to a point in the display area with zoom level 4.
image-B.png 15,187 73,187 73,52 15,52 IMAGE image-A.png Link from image-B file to invoke image-A.
image-C.png 30,8 10,8 10,7 30,7 SEARCH reaction:c1,reaction:c2 A link from image-C to results of a search query pointing to interactions c1 and c2.


The coords.json file structure:

  • filename - linked image file.

  • links - an array describing a link between image in filename with imageLinkFilename, query or modelLinkFilename.

    • polygon - the coordinates of the polygon which will be treated as an active area for the link. Provide absolute coordinates of the pixels in the corresponding image.

    • imageLinkFilename - links to other image form uploaded set, provide file’s name.

    • query - link to the results of a search query, provide the query.

    • modelLinkFilename - link to the main map, or one of the submaps.

      • zoomLevel - in case of linking to modelLinkFilename - this field should contain a number corresponding to the zoom levels in the display area; otherwise it should be left empty. The the furthest zoom out has number 0, each zoom in increases the zoom number by one. Smaller maps will have less zoom levels than big ones. Try uploading the map without images first, and assess the coordinates and zoom levels for the version with images.

      • modelPoint - in case of linking to modelLinkFilename - this field should contain absolute coordinates of the point in the target map, otherwise it should be left empty.


Example of a coords.json file:

[
   {
      "filename":"test.png",
      "links":[
         {
            "polygon":[
               {
                  "x":10.0,
                  "y":10.0
               },
               {
                  "x":100.0,
                  "y":10.0
               },
               {
                  "x":100.0,
                  "y":100.0
               },
               {
                  "x":10.0,
                  "y":100.0
               }
            ],
            "imageLinkFilename":"sub_image.png"
         },
         {
            "polygon":[
               {
                  "x":120.0,
                  "y":120.0
               },
               {
                  "x":150.0,
                  "y":150.0
               },
               {
                  "x":120.0,
                  "y":150.0
               },
               {
                  "x":150.0,
                  "y":120.0
               }
            ],
            "query": "s3,reaction:re1"
         }
      ]
   },
   {
      "filename":"sub_image.png",
      "links":[
         {
            "polygon":[
               {
                  "x":200.0,
                  "y":200.0
               },
               {
                  "x":200.0,
                  "y":400.0
               },
               {
                  "x":400.0,
                  "y":400.0
               },
               {
                  "x":400.0,
                  "y":200.0
               }
            ],
            "zoomLevel":1,
            "modelPoint":{
               "x":10.0,
               "y":100.0
            },
            "modelLinkFilename":"main.xml"
         }
      ]
   }
]



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