About#

Licensing#

MINERVA Platform is released under the Affero General Public License (AGPL).

Source code#

The source code for the MINERVA platform is currently available on the GitLab repository of the Bioinformatics Core of LCSB.

Important repositories#

core

code of the backend of the MINERVA Platform, its database and handlers of systems biology diagrams

frontend

code of the frontend of the MINERVA Platform, its web-based user interface

Reporting issues#

We greatly appreciate feedback about issues, or feature requests. The best way to do it is by submitting an issue. Issues or requests related to:

• User interface, map display:
  use the frontend issue tracker
• Platform functionality, format handling, webserver performance:
  use the core issue tracker
• When in doubt, use the core issue tracker, we will sort it out.

In many cases, in browser issues will allow you to directly submit an issue. These are handled by us and assigned to an appropriate issue tracker.

Supported projects#

The MINERVA Platform supports the following projects:

• Ageing map
• Asthma map
• Atlas of Inflammation Resolution
• BIOMAP
• CardioMap
• Chronic Inflammatory Diseases
• COVID-19 Disease Map
• Cystic fibrosis
• Expobiome Map
• imSAVAR Adverse Outcome Pathway maps
• ImmUniverse
• MIRIADE
• ONTOX
• Parkinson’s disease map
• PathwayLab
• Recon map
• Sarcopenia
• Rheumatoid arthritis map

Sources#

MINERVA relies on these following external data sources:

ChEMBL

The ChEMBL database in 2017. Gaulton A et al. PubMed ID: 27899562Nucleic Acids Res. 2017 Jan 4; 45(Database issue): D945–D954.

CTDbase

The Comparative Toxicogenomics Database: update 2019. Davis AP et al. PubMed ID: 30247620Nucleic Acids Res. 2019 Jan 8;47(D1):D948-D954. doi: 10.1093/nar/gky868.

DrugBank

DrugBank 4.0: shedding new light on drug metabolism. Law V et al. PubMed ID: 24203711Nucleic Acids Res. 2014 Jan;42(Database issue):D1091-7. doi: 10.1093/nar/gkt1068.

mirTarBase

Tools and data services registry: a community effort to document bioinformatics resources. Ison J et al. PubMed ID: 26538599Nucleic Acids Res. 2016 Jan 4;44(D1):D38-47. doi: 10.1093/nar/gkv1116.

OpenTargets

Open Targets Platform: new developments and updates two years on. Carvalho-Silva D et al. PubMed ID: 30462303Nucleic Acids Res. 2019 Jan 8;47(D1):D1056-D1065. doi: 10.1093/nar/gky1133.